Actualidad

Fecha: 20 de diciembre; 11,30h.

Lugar: Sala de tercer ciclo. Edificio de los Magnolios, 1ª planta.

Resumen: Based on preventive and precautionary dictates, the availability of procedures to detect increased morbidity rates in relatively small populations or clusters of rare diseases stands paramount. In this context, cost-aware, instructive and timely analyses must provide guidance thereby determining whether cases relate causally and the nature of their causal mechanisms. In addition, these analyses must indicate whether further assessments are needed and/or if any active environmental intervention in the pertinent community is required. Genuine aggregates of infrequent chronic diseases may be rendered biased or unnoticed by just measuring general secular trend statistics. Discretionary surveillance of these conditions entails the appearance of incidental clusters and costly supervening elucidation. In the foreground of the present study lies a report of ascending secular trends for leukaemias of myeloid lineage (MMs), in a province of 730,000 people. This warrants an inquiry plan aimed at unveiling causative clues. The main aim of this talk is to demonstrate the use of a sequential-based approach in detecting an elevated rate that may have initiated at some unknown point of time during the study period.

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