MIRIAM OSES RUIZ
INVESTIGADOR RAMON Y CAJAL

• Department: AGRONOMÍA, BIOTECNOLOGÍA Y ALIMENTACIÓN
• Area: Producción Vegetal
• e-mail: miriam.osesunavarra.es
• Phone number: (+34) 948 16 8433 (ext. 8433)
•   INSTITUTO DE AGROBIOTECNOLOGIA

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Dr. Miriam Oses-Ruiz, graduated in Agricultural Engineering (UPNA, Spain) and obtained an MSc in Plant Pathology (Wageningen University, NL). As a pre-doctoral graduate, she worked with Prof. Jan van Kan (Wageningen University, NL) and Prof. Sophien Kamoun FRS (The Sainsbury Laboratory, UK) carrying research in fungal biology, effector biology and plant immunity with an Erasmus Mundus fellowship.  In 2010, she joined the laboratory of Prof. Nick Talbot FRS (University of Exeter, UK) as a Marie Curie Fellow to carry her PhD. After a post-doctoral period at University of Exeter, she moved as a senior post-doctoral fellow to The Sainsbury Laboratory. During that time, she investigated the biology of the rice blast fungus, Magnaporthe oryzae, specialising in transcriptomics, phosphoproteomics, ChIP-seq, genetics, cell cycle biology and molecular biology. She participated in an ITN Marie-Curie project, 3 BBSRC projects (UK) and one ERC project, and produced more than 15 publications in international peer review journals including PNAS, Science, eLIFE, Nature and Nature Microbiology (87% in Q1; 3 Multidisciplinar; 13% in Q2).

In 2021, she obtained a "Retos de Investigation JIN" from “Agencia Estatal de Investigacion” as independent research post-doctoral fellow and joined UPNA. Afterwards she was awarded with an Andia Senior Talent fellowship to set up her own research program. In 2022, she obtained a Ramon y Cajal fellow and build the research line and team called “Molecular Biology of Fungi”. The aim of MBF is to investigate the molecular mechanisms associated with infection caused by fungal pathogens. In MBF we investigate the blast fungus Magnaporthe oryzae and the research program is based in three main areas: 1) cell cycle regulation and DNA damage; 2) transcriptional regulatory networks; 3) cellular heterogeneity.

MBF research group has been funded by several grants including Agencia Estatal de Investigacion to investigate the molecular mechanisms associated with cell cycle-mediated infection. In that grant we collaborated with several groups, Dr. Frank Menke (TSL, UK) and Prof. Nick Talbot TSL, UK), unravelling the phosphorylation landscape and transcriptional network associated with appressorium -mediated plant infection and determine that our kinase of interest, Cds1, is tightly linked with MAPK signalling. Dr. Oses-Ruiz also received funging European Research Council with a Starting Grant where she proposed to elucidate and understand at the molecular level the factors contributing to generate cellular heterogeneity driving infection in the blast fungus. 

Dr. Oses-Ruiz holds a solid network of collaborators from the UK, USA, Japan, Spain, and The Netherlands. She have actively cooperated in disseminating our research and engage with the general public by carrying several radio interviews, podcast and attending events. Our work has been presented in more than 50 scientific meetings, and since becoming independent, Miriam has been invited to several conference and meetings as a speaker, including the 31^st Fungal Genetics Conference (USA, 2022), Molecular Dialogue in Plant Biotic Interactions (France, 2023), British Mycological Society (UK, 2025) and International Fungal Biology Conference (IFBC) (Greece, 2025).  She was an Assistant Feature Editor of Plant Physiology journal (2022-2024), a Guest Co-Editor of Frontiers special issue “Fungal Biology” (2022) and a reviewer for Molecular Microbiology, PLoS Genetics, Molecular Plant Pathology, Microbiology Spectrum, Molecular Plant Microbe Interactions and Fungal Biology Reviews.