Universidad Pública de Navarra - Nafarroako Univertsitate Publikoa
Public University of Navarre
| Course code: 501005 | Subject title: MOLECULAR FARMING: PLANTS AS BIOFACTORIES | ||||
| Credits: 3 | Type of subject: Optative | Year: 4 | Period: 1º S | ||
| Department: Agronomía, Biotecnología y Alimentación | |||||
| Lecturers: | |||||
| VERAMENDI CHAROLA, JON MIRENA (Resp) [Mentoring ] | |||||
Contents
Transgenic plants.
Plants as chemical and pharmaceutical factories
Production technology
Legal framework and biosecurity of molecular farming production.
General proficiencies
TC1: Ability to develop activities in the field of Rural and Agrifood Engineering, assuming a social, ethical, and environmental commitment.
TC2 Oral and written communication skills.
TC6 Ability to learn autonomously.
TC7 Ability to solve problems with creativity, initiative, methodology, and critical thinking.
Specific proficiencies
SC12: Ability to recognize and utilize the base principles of animal production. Ability to define and design livestock facilities.
SC18: Ability to transfer technology; understand, interpret, communicate, and adopt advances in the field of agriculture.
Learning outcomes
R1- To know, understand and apply the molecular underpinnings and biotechnological techniques in the production of recombinant proteins in plants.
R2- To know the applications of the molecular farming
R3- To know the legal framework and biosecurity issues of products obtained by molecular farming
Methodology
| Methodology - Activity | Classroom hours | Non-classroom hours |
| A-1 Lectures | 5 | |
| A-2 Practice | ||
| A-3 Debates, knowledge pooling, group mentoring | ||
| A-4 Homework | 15 | |
| A-5 Reading Material | 38 | |
| A-6 Personal study | 15 | |
| A-7 Exams, assessment tests | 2 | |
| A-8 Indivual mentoring | ||
| ¿ | ||
| Total | 2 | 73 |
Evaluation
Knowledge of the basic concepts of the subject: answering of questionnaires for each of the presented topic (50%).
Preparation of a individual presentation on a scientific article (40%).
Participation in discussion forums and use of tutorials (10%).
Agenda
0 - Transgenic plants: concept and methods of plant transformation.
1 - Plants as chemical and pharmaceutical factories: production of therapeutic proteins, antibodies, vaccines, enzymes and proteins of industrial use.
2 - Recommended crops on molecular farming: mono - or dicotyledons; annual or perennial; biomass index; production on leaf crops, seeds or fruits.
3 - Production technology: stable or transient expression; expression in nucleus or plastids; expression with viral vectors or agroinfiltracion; bioreactors; systems to optimize the expression of the transgene.
4 - Post-translational modifications of biopharmaceutical compounds produced in plants. Molecular farming and enterprise.
5 - Legal framework and biosecurity of molecular farming production.
Bibliography
Access the bibliography that your professor has requested from the Library.
Basic bibliography:
Genoma España. Plantas biofactoría: informe de vigilancia tecnológica. 2005.
Complementary bibliography:
Christou P y Klee H. Handbook of plant biotechnology (volume 2). Editorial John Wiley and Sons, Ltd. 2004.
Erickson L, Yu WJ, Brandle J y Rymerson R. Molecular farming of plants and animals for human and veterinary medicine. Editorial Kluwer Academic Publishers. 2002.
Faye L y Gomord V. Recombinant proteins from plants. Editorial Humana Press. 2009.
Fischer R y Schillberg S. Molecular farming: plant-made pharmaceuticals and technical proteins. Editorial Wiley-VCH Verlag GmbH. 2004.
Hammond BG. Food safety of proteins in agricultural biotechnology. Editorial CRC Press. 2008.
Hood EE y Howard JA. Plants as factories for protein production. Editorial Kluwer Academic Publishers. 2002.
Walsh G. Biopharmaceuticals: biochemistry and biotechnology (2nd edition). Editorial John Wiley and Sons, Ltd. 2003.